Table 1.
SV40 neutralizing antibody positivity among Colombian and Nicaraguan subject groups
| Country | Groupa | Group criteria | Total subjects | No. SV40 antibody positive (%)b | SV40 neutralizing antibody titers (median) |
|---|---|---|---|---|---|
| Colombia | A | Cervical cancer patients | 70 | 12 (17.1) | 1:20–1:200 (1:20) |
| B | Matched cancer controls | 70 | 7 (10.0) | 1:20–1:1000 (1:80) | |
| C | General population | 320 | 77 (24.1) | 1:10–1:1000 (1:20) | |
| D | Sex workers | 57 | 22 (38.6) | 1:10–1:100 (1:40) | |
| Total (Groups A-D): | 517 | 118 (22.8) | 1:10–1:1000 (1:20) | ||
| Nicaragua | E | Endoscopy patients | 149 | 19 (12.8) | 1:10–1:200 (1:20) |
Sample collection dates: Groups A–C, 1968; Group D, 1970; Group E, 2010.
Statistical significance: Group C vs. Groups A+B, p = 0.0131; Group D vs. Group C, p = 0.0185; Groups A–D (Total) vs. Group E, p = 0.0143; Group C vs. Group E, p = 0.0099; Group C-(vbc) vs. Groups A+B, p = 0.0039. (vbc) = Birth cohort that contains potential vaccinees (birth dates 1949–1960).