Fig. 4.

PvMSP8-specific MBC responses at 4 years post-infection. The numbers of specific MBCs produced in response to a PvMSP8, b tetanus toxoid (TT), and total IgG in PBMCs from subjects that persisted 4 years after the P. vivax infection were determined using an ELISPOT assay (n = 13). The frequencies of MBCs were determined by counting the number of spots that appeared per million cultured PBMCs. Each symbol represents the MBC number for one individual. The line represents the median value