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. 2019 May 31;20:439. doi: 10.1186/s12864-019-5803-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — DNA methylation dynamics of major repeat classes during human pre-implantation. a Box-plot representations of DNA methylation levels from single cells across stages of pre-implantation categorised by repeat classes. b DNA-methylation and expression correlation heat-map. Each cell in the heat-map represents r-correlation coefficients between the average expression levels obtained from a single cell dataset [36] and average methylation levels for another single cell dataset [76] for all members of a given repeat class in the specified time-frame during pre-implantation