Fig. 3.

Body composition and energy expenditure. Data are presented as mean ± standard deviation. Subjects were instructed to consume 20% of their estimated total energy needs from the assigned study oil over the 4-month treatment period. a) There was no difference between groups and no change in body weight over the course of the treatment period. Fat free mass (FFM) and fat mass (FM) are similar between groups at baseline (not shown) and at the end of study (b). c) Resting energy expenditure per kg of fat free mass (FFM) and d) Total energy expenditure per kg of FFM was not different between groups at the end of study. e) Respiratory quotient (VCO₂/VO₂) was similar between groups. RQ ranged from 0.8 to 1.0 after 10-h overnight fast suggesting participants were oxidizing a mix of carbohydrates and fat at rest. f) Lipid deposition of soleus intra-myocellular (IMCL) and extra-myocellular (EMCL) did not change over the course of the treatment period but liver lipid deposition significantly decreased in the C7 group compared to C8. g) There was no difference in oxidation of the ¹³C–oleic acid between groups. Label recovery peaked in all subjects about 4 to 6 h after the meal and returned toward baseline 12 h after the meal. There was no difference in RQ or oleic acid oxidation after the moderate intensity treadmill between treatment groups performed between 7 and 8 h after the oral load. h) Total fat oxidation was dramatically lower among subjects with an FAO disorder compared to published normal controls (18)