Table 3.
Association between pre-treatment adherence to the Pro-Fertility Diet, the Mediterranean Diet, the Alternate Healthy Eating Index 2010, and the Fertility Diet and probability of implantation, clinical pregnancy, and live birth following ART in the EARTH Study.
| Adjusted Proportions (95% CI)1 |
||||
|---|---|---|---|---|
| Women/Cycles | Implantation | Clinical Pregnancy | Live Birth | |
| Pro-Fertility Diet | ||||
| Q1 (11-20) | 103/182 | 0.46 (0.39, 0.54) | 0.40 (0.33, 0.48) | 0.33 (0.26, 0.40) |
| Q2 (21-23) | 90/165 | 0.53 (0.45, 0.61) | 0.46 (0.38, 0.54) | 0.32 (0.25, 0.40) |
| Q3 (24-25) | 78/123 | 0.65 (0.56, 0.73)* | 0.59 (0.50, 0.68)* | 0.48 (0.39, 0.57)* |
| Q4 (26-32) | 86/138 | 0.68 (0.59, 0.76)* | 0.61 (0.52, 0.69)* | 0.56 (0.47, 0.64)* |
| P for trend | <0.001 | <0.001 | <0.001 | |
| Mediterranean Diet | ||||
| Q1 (17-28) | 90/170 | 0.49 (0.41, 0.57) | 0.43 (0.35, 0.50) | 0.31 (0.25, 0.39) |
| Q2 (29-31) | 93/150 | 0.62 (0.53, 0.69)* | 0.56 (0.47, 0.64)* | 0.47 (0.39, 0.55)* |
| Q3 (32-33) | 74/123 | 0.64 (0.55, 0.72)* | 0.57 (0.48, 0.66)* | 0.44 (0.36, 0.53)* |
| Q4 (34-44) | 100/165 | 0.55 (0.47, 0.63) | 0.48 (0.40, 0.56) | 0.41 (0.34, 0.49) |
| P for trend | 0.17 | 0.25 | 0.06 | |
| Alternate Healthy Eating Index 2010 | ||||
| Q1 (32-60) | 92/158 | 0.62 (0.54, 0.69) | 0.55 (0.47, 0.63) | 0.44 (0.36, 0.52) |
| Q2 (61-67) | 87/151 | 0.59 (0.50, 0.67) | 0.51 (0.43, 0.59) | 0.42 (0.34, 0.50) |
| Q3 (68-74) | 88/148 | 0.53 (0.44, 0.61) | 0.50 (0.42, 0.59) | 0.40 (0.33, 0.49) |
| Q4 (75-99) | 90/151 | 0.54 (0.46, 0.62) | 0.45 (0.37, 0.53) | 0.37 (0.29, 0.45) |
| P for trend | 0.12 | 0.08 | 0.19 | |
| Fertility Diet | ||||
| Q1 (13-22) | 99/168 | 0.54 (0.46, 0.62) | 0.48 (0.41, 0.56) | 0.37 (0.30, 0.45) |
| Q2 (23-25) | 93/168 | 0.58 (0.50, 0.66) | 0.53 (0.45, 0.60) | 0.42 (0.35, 0.50) |
| Q3 (26-28) | 89/145 | 0.62 (0.53, 0.69) | 0.52 (0.44, 0.61) | 0.42 (0.34, 0.50) |
| Q4 (29-35) | 76/127 | 0.54 (0.45, 0.63) | 0.47 (0.39, 0.56) | 0.43 (0.34, 0.52) |
| P for trend | 0.83 | 0.89 | 0.37 | |
1
Analyses were run using generalized linear mixed models with random intercepts, binomial distribution, and logit link function. Data are presented as predicted marginal proportions (95% CI) adjusted for calorie intake, age, BMI, smoking status, and moderate to vigorous exercise.
*
P-value < 0.05 for comparison of specific quartile versus quartile 1 (reference).