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. Author manuscript; available in PMC: 2020 Jun 30.
Published in final edited form as: Biochem Biophys Res Commun. 2019 May 12;514(3):998–1003. doi: 10.1016/j.bbrc.2019.05.045

Fig. 3. Eight weeks of treatment with NLRP3 inhibitor, MCC950, improved heart function in GPER knockout mice.

Fig. 3.

MCC950 treatment increased %fractional shortening (FS) (A), increased e΄ (B), decreased E/e΄ (C), determined by echocardiography, and decreased cardiac ANF (D) and BNP (E) mRNA determined by real-time PCR. n=6/group. * P <0.05 vs vehicle treated GPER knockout mice.