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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Muscle Nerve. 2018 Nov 26;59(2):201–207. doi: 10.1002/mus.26335

Table 1.

Baseline Characteristics.

Item Rasagiline Treated Rasagiline Controls Historical Controls41,42 p-value*
Number participants 60 20 177
Number female (%) 20 (33%) 7 (35%) 65 (37%) 0.89
Number bulbar onset (%) 10 (17%) 3 (15%) 44 (25%) 0.29
Number taking riluzole (%) 49 (82%) 16 (80%) 121 (68%) <.001
Mean age in years (SD/range) 58.4 (10.2 / 28–75) 57.5 (8.5 / 40–73) 57.3 (11.0 / 30–80) 0.22
Mean symptom duration years (SD/range) 1.23 (0.49 / 0.43–2.04) 1.37 (0.46 / 0.52–2.05) 1.06 (0.46 / 0.23–2.0) 0.004
Mean baseline % predicted vital capacity (SD/range) 92.5 (12.3 / 73–122) 94.4 (12.5 / 75–124) 94.9 (15.3 / 75–178) 0.52
Mean baseline ALSFRS-R (SD/range) 38.2 (6.1 / 17–48) 35.9 (7.5 / 14–45) 38.7 (4.8 / 23–47) 0.08
*

P-value for 3 way ANOVA comparing treated, controls, and historical controls.