Table 2.
Summary of the effect of ancestral DEHP exposure on hippocampal and amygdala gene expression in F3 males and females.
| Males | Females | |
|---|---|---|
| Gene Name | Hippocampus | |
| Esr2 | NC | NC |
| Nr3c1 | NC | NC |
| Dnmt3a | NC | NC |
| Gene Name | Amygdala | |
| Esr1 | NC |
Down-regulated (200 μg/kg/day- and 500 mg/kg/day-treatment lineages) |
| Esr2 |
Up-regulated (20 μg/kg/day- and 200 μg/kg/day-treatment lineages) |
NC |
| Ar | NC | NC |
| Nr3c1 | NC | NC |
| Nr3c2 | NC |
Down-regulated (200 μg/kg/day-treatment lineage) |
| Crhr1 | NC | NC |
| Crhr2 | NC | NC |
| Mc4r | NC | NC |
| Drd1 |
Up-regulated (20 μg/kg/day- and 750 mg/kg/day-treatment lineages) |
NC |
| Drd2 | NC |
Down-regulated (20 μg/kg/day- and 750 mg/kg/day-treatment lineages) |
| Dnmt1 | NC | NC |
| Dnmt3a | NC | NC |
| Dnmt3b | NC | NC |
| Dnmt3l | NC | NC |
| Mecp2 | NC | NC |