Table 1.

Infant Clinical Characteristics^a

Infant	GA, wk	CA at TMS Assessment	Neuroradiology Findings	GMA Findings	Clinical Motor Outcomes
1	31	13 wk	Bilateral parieto-occipital cystic PVL	Absent fidgety movements	Spastic QCP
2b	36	12 mo	Left parietal encephalomalacic cleft, similar but milder cleft on right parietal vertex; hemosiderin deposits in left temporal, posterior left frontal, and left parietal lobes	Fidgety movements	No observable motor impairments, no CP diagnosis
3	26	18 wk	Bilateral cystic PVL, ex vacuo dilatation of the lateral and third ventricles; left thinning of parietal and occipital lobes	Absent fidgety movements	Spastic QCP
4	22	9 mo	Bilateral cerebellar hemorrhages, ex vacuo dilatation of the fourth ventricle	Too old at exam	Gross motor delays, DEA = 3 mo 2 d; no CP diagnosis
5	39	10 mo	Extensive bilateral ischemia in the right parietal, occipital, temporal, and posterior frontal lobes; BG and Thal; and in left parietal, posterior temporal, posterior occipital, and frontal lobes	Too old at exam	HCP, left upper and lower limb impairment, DEA = 4 mo
6	41	12 mo	Gliosis and encephalomalacia along the right paracentral region, corona radiata, centrum semiovale, and PLIC	Too old at exam	HCP, left upper limb impairment, DEA = 10 mo

^a BG = basal ganglia; CA = corrected age; CP = cerebral palsy; DEA = developmental equivalent age from Bayley-III fine motor subscale; GA = gestational age; GMA = General Movements Assessment; HCP = hemiplegic cerebral palsy; PLIC = posterior limb of internal capsule; PVL = periventricular leukomalacia; QCP = quadriplegic cerebral palsy; Thal = thalamus; TMS = transcranial magnetic stimulation.

^b Infant had prior GMA at age CA 13 wk. Centrally acting medications: Infant 3: amlodipine, clonidine, valium, gabapentin, melatonin; Infant 5: phenobarbital.