Figure 4.

Functional and pathway analysis of IQCJ-SCHIP1-AS1 in CRC. (A,B) GO annotations (A) and KEGG pathway (B) of the top DEGs potentially regulated by IQCJ-SCHIP1-AS1 were analysed in R software. (C) GSEA of the top DEGs was performed in GSEA v3 software. (D) Several key DEGs in these significantly related pathways were validated by qRT-PCR. *, P<0.05; **, P<0.01. IQCJ-SCHIP1-AS1, IQCJ-SCHIP1 antisense RNA 1; CRC, colorectal cancer; qRT-PCR, quantitative RT-PCR; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genome; DEG, differential expression gene.