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. 2019 May;7(9):207. doi: 10.21037/atm.2019.04.37

Table 1. Somatic mutations detected by NGS.

Gene c.HGVS g.HGVS Exon/intron Allele frequency (%)
TP53 c.524G>A p.R175H EX5 33.8
EGFR c.2573T>G p.L858R EX21 33.0
EGFR c.2153T>A p.L718Q EX18 1.3

NGS, next-generation sequencing. c.HGVS, Human Genome Variation Society CDNA reference sequence (represented by prefix ā€œcā€); g.HGVS, Human Genome Variation Society Genomic reference sequences (represented by the prefix ā€œgā€).