Table 1. Somatic mutations detected by NGS.
Gene | c.HGVS | g.HGVS | Exon/intron | Allele frequency (%) |
---|---|---|---|---|
TP53 | c.524G>A | p.R175H | EX5 | 33.8 |
EGFR | c.2573T>G | p.L858R | EX21 | 33.0 |
EGFR | c.2153T>A | p.L718Q | EX18 | 1.3 |
NGS, next-generation sequencing. c.HGVS, Human Genome Variation Society CDNA reference sequence (represented by prefix ācā); g.HGVS, Human Genome Variation Society Genomic reference sequences (represented by the prefix āgā).