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. 2019 Jun 3;5:32. doi: 10.1038/s41378-019-0064-3

Table 2.

Comparison of acoustofluidic separation methods

Type Advantages Disadvantages Applications
Bulk acoustic waves14,19,69,70 Simple device architectures; high throughputs Difficulties in handling nanoparticles; cooling required due to excessive heat Platelet separation; plasmapheresis; blood processing
Standing surface acoustic waves11,71,79,80 High precision; easy to miniaturize; strong acoustic radiation force Low throughput Nanoparticle separation; rare cell separation
Traveling surface acoustic waves75–82 High precision; easy to miniaturize; single IDT required Low throughput; design consideration to prevent standing wave formation Nanoparticle separation; fluorescence-activated cell sorting