Table 6.
Maternal vitamin D level and Fok1 genotype distribution between A cyanotic and Cyanotic CHD.
| A cyanotic CHD n = 37 | Cyanotic CHD n = 13 | P-value | ||
|---|---|---|---|---|
| Maternal vitamin level; nmol/La | ||||
| Median (IQR) | 31 (15–65) | 14 (8–28) | 0.000∗ | |
| Min-Max | 10–78 | 6.5–30 | ||
| Maternal vitamin D status; n (%)b | ||||
| Deficient n = 24 | 12 (50) | 12 (50) | 0.01∗ | |
| Insufficient n = 17 | 15 (88.2) | 2 (11.8) | ||
| Inadequate n = 6 | 6 (100) | 0 (0) | ||
| Sufficient n = 3 | 3 (100) | 0 (0) | ||
| Fok1 genotype; n (%)b | ||||
| F/F | n = 20 | 12 (60) | 8 (40) | 0.18* |
| F/f | n = 24 | 20 (83.3) | 4 (16.7) | |
| f/f | n = 6 | 5 (83.3) | 1 (16.7) | |
| Fok1 allele; n (%)c | ||||
| F | n = 64 | 44 (68.7) | 20 (31.3) | 0.05* |
| f | n = 42 | 36 (85.7) | 6 (14.3) | |
Statistical analysis: a, Mann–Whitney test; b, Fisher's exact test; c, chi square test.
CHD, congenital heart defects; IQR, interquartile rang.
*Significance at P ≤ 0.05.