Table 4. Factors associated with PAD (Univariate and multivariate regression analysis of 457 study patients).
| Univariate | Multivariate |
|||||
|---|---|---|---|---|---|---|
| |
Model 1 |
Model 2 |
||||
| Odds ratio (95%CI) | P value | Odds ratio (95%CI) | P value | Odds ratio (95%CI) | P value | |
| PAD | ||||||
| Age (per 10 yrs increase) | 1.96 (1.33–2.91) | 0.001 | 1.71 (1.11–2.66) | 0.016 | ----- | NS |
| Male gender | 1.35 (0.64–2.83) | 0.432 | ----- | NS | ||
| BMI (per 1 kg/m2 increase) | 0.97 (0.90–1.06) | 0.527 | ----- | NS | ||
| Hypertension | 5.76 (1.75–18.9) | 0.004 | 4.36 (1.30–14.6) | 0.017 | 3.96 (1.17–13.4) | 0.027 |
| Diabetes mellitus | 1.78 (0.91–3.48) | 0.095 | ----- | NS | ||
| Smoking | 2.31 (1.21–4.43) | 0.011 | 2.51 (1.27–4.98) | 0.008 | ----- | NS |
| LDL-C (per 10 mg/dL increase) | 1.03 (0.93–1.14) | 0.577 | ----- | NS | ||
| LDL-C lowering drug | 2.12 (1.11–4.03) | 0.023 | ----- | NS | ||
| TG (per 10 mg/dL increase) | 1.02 (0.97–1.07) | 0.428 | ----- | NS | ||
| TG lowering drug | 1.44 (0.48–4.33) | 0.513 | ----- | NS | ||
| HDL-C (per 10 mg/dL increase) | 0.69 (0.53–0.90) | 0.007 | ----- | NS | ||
| Betatrophin (per 100 mg/dL increase) | 1.11 (1.05–1.16) | < 0.001 | 1.07 (1.01–1.13) | 0.028 | 1.09 (1.03–1.15) | 0.002 |
| CAD | 5.95 (2.45–14.4) | < 0.001 | 4.56 (1.84–11.3) | 0.001 | ||