Table 1. Characteristics of study patients.
Characteristics | PA user | Non-PA user | P value |
---|---|---|---|
n = 401) | (n = 1461) | ||
Age (years) | 70.8 ± 12.5 | 68.7 ± 13.4 | 0.007 |
Men (n, %) | 224 (55.9) | 828 (56.7) | 0.782 |
Hypertension (n, %) | 325 (81.0) | 1078 (73.8) | 0.005 |
Diabetes mellitus (n, %) | 153 (38.2) | 439 (30.0) | 0.007 |
History of CAD (n, %) | 22 (5.5) | 33 (2.3) | < 0.001 |
Atrial fibrillation (n, %) | 61 (15.2) | 145 (9.9) | 0.005 |
Cigarette smoking (n, %) | 166 (41.4) | 569 (38.9) | 0.412 |
Hyperlipidemia(n, %) | 230 (57.4) | 716 (49.0) | 0.005 |
Systolic blood pressure (mm Hg) | 150.2 ± 17.8 | 142.6 ± 20.7 | < 0.001 |
Diastolic blood pressure (mm Hg) | 90.2 ± 14.5 | 88.9 ± 16.8 | 0.152 |
Glucose (mM) | 6.9 ± 2.5 | 6.6 ± 2.8 | 0.047 |
Hemoglobin A1c (%) | 6.6 ± 1.9 | 6.2 ± 2.1 | < 0.001 |
Onset to admission time (h) | 18.8 ± 10.6 | 19.6 ± 11.3 | 0.178 |
Stroke subtype (n, %) | 0.008 | ||
Atherothrombosis | 193 (48.1) | 775 (53.0) | |
Small artery disease | 96 (23.9) | 395 (27.0) | |
Cardioembolism | 112 (27.9) | 291 (19.9) | |
Prestroke treatment (n, %) | |||
Previous statins | 80 (20.0) | 235 (16.1) | 0.072 |
Antihypertensive | 297 (74.1) | 1052 (72.0) | 0.453 |
Hypoglycemic | 119 (29.7) | 403 (27.6) | 0.451 |
Antithrombotic therapy in the acute phase (n, %) | |||
Thrombolysis (n, %) | 41 (10.2) | 142 (9.7) | 0.773 |
Clopidogrel alone | 108 (26.9) | 354 (24.9) | 0.284 |
Aspirin alone | 81 (20.2) | 338 (23.1) | 0.247 |
Clopidogrel plus aspirin | 107 (26.7) | 371 (25.4) | 0.665 |
Anticoagulants | 62 (15.5) | 235 (16.1) | 0.761 |
PA, prestroke aspirin; CAD, coronary artery disease.