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. Author manuscript; available in PMC: 2019 Jun 3.
Published in final edited form as: Int J Oncol. 2010 Oct;37(4):963–971. doi: 10.3892/ijo_00000747

Figure 1.

Figure 1.

Tumor growth inhibition by zebularine and DAC in cells with silenced but not deleted CDKN2A. (A) Effect of zebularine on growth of lung cell lines H2228, H226 with deleted and H719 and H865 with silenced CDKN2A following a four-day treatment. (B) Effect of DAC on growth of lung cell lines H2228 and H226 with deleted and H719 and H865 with silenced CDKN2A. Lung cancer cells were treated with DAC (0.25–3.0 μM) for 72 h followed by 24 h incubation without drug. The data shown represent the mean ± SD of 3–5 experiments. (C) Effect of zebularine on growth of breast cancer cell lines MDA-MB231 with deleted and MDAMB435 with silenced CDKN2A following a four-day treatment.