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. 2018 May 18;25(7):958–967. doi: 10.1177/1352458518775303

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© The Author(s), 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — CSF NfL levels in CIS-CDMS adults and children with and without T1-hypointense lesions on baseline MRI. (a) Adults: T1-hypointense lesions versus no T1-hypointense lesions on baseline MRI. (b) Children: T1-hypointense lesions versus no T1-hypointense lesions on baseline MRI. Horizontal lines with error bars indicate geometric mean with 95% CI.

NfL: neurofilament light chain; pg/mL: picogram/millilitre; CDMS: clinically definite multiple sclerosis.