Table 1.
Patients and disease characteristics at baseline.
| Characteristics |
n = 60 |
||
|---|---|---|---|
| N0 | % | ||
| Age, years | |||
| Median | 54 | ||
| Range | 26–74 | ||
| Breast primary tumor size, mm | |||
| Median | 61 | ||
| Range | 15–120 | ||
| Serum menopausal status | |||
| Premenopausal | 22 | 37 | |
| Postmenopausal | 38 | 63 | |
| Clinical nodal stage | |||
| cN0 | 29 | 48 | |
| cN1 + cN2 | 31 | 52 | |
| Clinical stage* | |||
| IIA | 11 | 18 | |
| IIB | 22 | 37 | |
| IIIA | 10 | 17 | |
| IIIB | 17 | 28 | |
| Tumor type | |||
| Invasive ductal | 60 | 100 | |
| Invasive lobular | 0 | ||
| Other | 0 | ||
| Tumor grade† | |||
| 2 | 31 | 52 | |
| 3 | 28 | 47 | |
| Missing | 1 | 2 | |
| Ki67 labeling index§ | |||
| <20 | 5 | 9 | |
| ⩾20 | 53 | 91 | |
| Steroid receptor status | |||
| ER or PgR-positive | 44 | 73 | |
| ER and PgR-negative | 16 | 27 | |
| HER2 | |||
| Positive by IHQ/FISH | 60 | 100 | |
| Family history of cancer | |||
| Any type of cancer | 13 | 22 | |
| Breast/ovarian cancer | 16 | 27 | |
| No family history | 31 | 52 | |
| Race | |||
| White | 25 | 42 | |
| Black | 12 | 20 | |
| Other | 23 | 38 | |
ER, estrogen receptor; FISH, fluorescence in situ hybridization; HER2, human epidermal growth factor receptor 2; IHC, immunohistochemistry; PgR, progesterone receptor.
*
TNM classification according to the International Union Against Cancer.
†
Grading according to Bloom–Richardson.
§
Immunohistochemistry was performed according to International guidelines.