Fig. 2.

Gene expression values in healthy, pre-diabetic and type 2 diabetics patients. Boxplots show log₂ gene expression values of key lipogenic genes according to the diabetic status. N: normal patients (n = 241), P: pre-diabetic patients (n = 319) and D: diabetic patients (n = 350). Genes are fatty acid elongase-6 (ELOVL6), stearoyl-CoA desaturase (SCD) and fatty acid synthase (FASN). The following P values and log₂ fold changes (log₂FC) were calculated from pairwise comparisons of diabetic vs normal patients: ELOVL6: log₂FC = 1.2, P = 8.4 × 10^{− 11}; SCD: log₂FC = 1.2, P = 2.2 × 10^{− 08} and FASN: log₂FC = 1.3, P = 4.8 × 10^{− 13}