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. 2019 Jun 3;20:298. doi: 10.1186/s12859-019-2906-2

Fig. 2.

Fig. 2

While C is the initial coverage (top), the expected number of reads that fully cover a selected k-mer is Ck. Depending on the insert size and the insert size variability, the left and right flanking regions that are covered by the paired reads have a coverage of Ck/2 or lower