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. 2019 Jun 3;20:298. doi: 10.1186/s12859-019-2906-2

Fig. 4.

Fig. 4

Real example of a k-mer frequency spectrum that is a superposition of two distributions corresponding to real and erroneous k-mers, respectively. A model of two Poisson distributions is fit to the data using the expectation-maximization algorithm. The coverage cutoff is established at the intersection of the two distributions