Effects of ADSC or Nrg4-ADSC transplantation on hepatic steatosis. (a)
Representative micrographs of HE and Oil Red O staining of the liver
tissue sections, (b, c) levels of total cholesterol (TC, B) and TG (C)
and in the plasma of the indicated mouse groups, and (d, e) the TC (d)
and TG (e) levels in the liver tissues of the indicated mouse groups. *:
compare with HFD, ***P < 0.001; #: compare with
ADSCs, #P < 0.05. ADSCs – HFD-fed mice
with ADSC infusion; HFD – HFD-fed mice without cell infusion; Nrg4-ADSC
– HFD-fed mice with Nrg4-ADSC infusion. ADSC: adipose tissue-derived
MSC; HFD: high-fat diet; Nrg4: neuregulin 4; TC: total cholesterol; TG:
triglyceride. (A color version of this figure is available in the online
journal.)