Table 2.

Zonulin and I-FABP levels in patients with IBS compared with healthy controls and celiac disease.

Biomarker	Celiac disease (n = 53)	IBS-D (n = 50)	IBS-C (n = 50)	Healthy controls (n = 42)
Zonulin levels* (ng/ml)	66.7 (55.2, 80.5)	65.8 (43.3, 93.4)	67.2 (44.2, 91.2)	45.2 (27.3, 61.5)
I-FABP levels* (pg/ml)	391.4 (217.1, 768.9)	224.1 (121.8, 384.9)	205.5 (99.4, 333.3)	338.2 (204.9, 479.0)

^*Values expressed as median (interquartile range).

IBS-C: constipation-predominant irritable bowel syndrome; IBS-D: diarrhea-predominant IBS; I-FABP: intestinal fatty acid binding protein.