Table 4.
Dependent variable: treatment failure at day 30 | ||||
---|---|---|---|---|
Univariate |
Multivariate (only remaining variables) |
95% confidence interval | ||
Variable | p-value | p-value | odds ratio | |
Age | 0.001 | 0.001 | 1.060 | 1.025–1.097 |
Gender | 0.546 | |||
ECOG status | 0.144 | |||
Immunosuppression | 0.093 | |||
Ribotype 027 | 0.766 | |||
Severe CDI | 0.374 | 0.083 | 0.311 | 0.083–1.166 |
Number of recurrences | 0.054 | 0.080 | 1.477 | 0.955–2.284 |
Antibiotic induction | 0.688 | |||
Proton pump inhibitor | 0.114 | |||
Antimotility agent | 0.925 | |||
Bowel lavage | 0.191 | |||
Frozen FMT preparation | 0.283 | |||
Route of application | ||||
Capsules | 0.093 | |||
Upper GIT | 0.214 | |||
Lower GIT | 0.254 |
CDI = Clostridioides difficile infection, ECOG = Eastern Cooperative Oncology Group, FMT = fecal microbiota transfer, GIT = gastrointestinal tract.