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. 2019 Jun 3;10:158. doi: 10.1186/s13287-019-1276-z

Table 6.

The advantages and potential limitations of EV therapy

Advantages

Lipid bilayer shell can avert proteolytic degradation;

EVs contain many potential regulatory components;

EVs can be applied to personalized medicine.

[129, 132134]
Potential limitations

Short-term effects because of short half-life;

Rapid clearance by the innate immune system;

Efficiency of EV uptake needs to be improved;

Administration routes of EVs must be appropriately selected.

[135138]