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Effect of Angong Niuhuang pill (ANP) on mRNA expression of IL-6, IL-17, IL-10, and TGF-β1 in the aorta. (a) mRNA levels of the proinflammatory cytokines IL-6 and IL-17. (b) mRNA levels of anti-inflammatory cytokines IL-10 and TGF-β1. The mRNA levels in ApoE−/− mice fed a high-fat diet were used as references. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001; P ∗∗∗∗ < 0.0001; P < 0.05 indicates significant difference.
