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. 2019 Jan 3;104(6):1209–1220. doi: 10.3324/haematol.2018.201483

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Figure 5. — Combination Index (CI) plot of ARV 825 with small molecule inhibitors. Synergistic growth inhibition (MTT assay) of KMS11 and KMS28BM multiple myeloma cells in the presence of ARV 825 and a small molecule inhibitor. CI defines interaction between ARV 825 and small molecule inhibitor as plotted against a fraction of cell viability. CI<1, CI=1, and CI>1 represent synergism, additive, and antagonism of the two compounds, respectively. Values of CI analysis are shown in Online Supplementary Table S3.