Table 3.
Cognition.
Predictors |
Outcomes |
||||||||
---|---|---|---|---|---|---|---|---|---|
Variables |
Animal fluency |
Delayed 90″ recall |
|||||||
FΔ | R2 Δ | Beta | Sig. | F Δ | R2 Δ | Beta | Sig. | ||
Final model | 19.498 | 0.162 | <0.001 | 11.534 | 0.103 | <0.001 | |||
Demographics | 85.575 | 0.117 | <0.001 | 47.562 | 0.069 | <0.001 | |||
Age | −0.252 | <0.001 | −0.162 | <0.001 | |||||
Sex | 0.002 | 0.927 | 0.149 | <0.001 | |||||
Living | −0.021 | 0.340 | −0.009 | 0.690 | |||||
PD severity | 17.693 | 0.024 | <0.001 | 12.180 | 0.017 | <0.001 | |||
Model | Resting tremor | −0.05 | 0.018 | 0.024 | 0.266 | ||||
H&Y stage | −0.115 | <0.001 | −0.081 | 0.001 | |||||
Disease duration | −0.008 | 0.733 | −0.057 | 0.017 | |||||
Medication | 6.631 | 0.015 | <0.001 | 4.653 | 0.011 | <0.001 | |||
Model | Levodopa | −0.067 | 0.004 | −0.047 | 0.048 | ||||
Dopamine agonist | 0.021 | 0.332 | 0.017 | 0.462 | |||||
Anti depressant | −0.017 | 0.434 | −0.008 | 0.731 | |||||
Stimulant | 0.012 | 0.562 | 0.025 | 0.245 | |||||
Cognitive enhancer | −0.093 | <0.001 | −0.092 | <0.001 | |||||
Comorbidity | 1.869 | 0.007 | 0.061 | 1.503 | 0.006 | 0.151 | |||
Model | Heart/circulation | −0.002 | 0.918 | −0.050 | 0.030 | ||||
Respiratory | −0.017 | 0.430 | 0.025 | 0.260 | |||||
Diabetes | −0.041 | 0.061 | −0.018 | 0.417 | |||||
Neurological | −0.035 | 0.098 | 0.000 | 0.992 | |||||
Cancer | −0.035 | 0.100 | 0.001 | 0.979 | |||||
Arthritis | −0.032 | 0.150 | 0.036 | 0.120 | |||||
BMI squared | −0.009 | 0.677 | −0.018 | 0.414 | |||||
BMI | 0.006 | 0.802 | −0.031 | 0.176 |
Results from separate hierarchical regression analyses examining the relationship between comorbidities and cognitive tasks (animal fluency and delayed memory recall). Variables pertaining to demographics, PD severity and medication status were statistically controlled for in preceding blocks of predictors.