Fig. 1.

miR-192–5p is upregulated in PCa. In the GSE21036 dataset, miR-192–5p was significantly upregulated in metastatic samples compared to primary tumor tissues (a), was upregulated in Gleason grades 6 (p < 0.05), 7 (p < 0.05), 8 and 9 (p < 0.001) PCa compared to normal tissues (b), and was overexpressed in patients with T2 (p < 0.05), T3 (p < 0.05), and T4 (p < 0.001) PCa compared to normal controls (c). In the TCGA dataset, miR-192 was significantly upregulated in PCa samples compared to matched normal samples (d, p < 0.01) and the BCR-free survival rates were higher in patients with low miR-192 (e). * p < 0.05; ** p < 0.01; *** p < 0.001.