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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Mater Sci Eng C Mater Biol Appl. 2019 Apr 12;102:75–84. doi: 10.1016/j.msec.2019.04.030

Figure 3.

Figure 3.

Effect of matrix mechanics on pro-angiogenic activity of MSCs. The concentration of (A) VEGF and (B) FGF and PDGF released by MSCs seeded on gels of different rigidity assayed via ELISA. (C) Effect of released angiogenic factors on proliferation of HUVECs. The proliferation of HUVECs in the presence of conditioned media was normalized with respect to that in presence of HUVECs media (control). (D) Typical images of sprout formation during Matrigel culture of HUVECs in presence of conditioned media as well as normal HUVEC growth media. (E) Quantitative analysis of sprouts formed. Mesh area formed by HUVECs in presence of conditioned media was normalized with respect to control (normal HUVEC growth media). Error bar S.E.M (N=3).