Table 6.
Transcript level changes of host CRISPR loci and cas genes of the subtype I-A CRISPR-Cas system of strain REY15A during coinfection. log2 fold-changes are shown in the early and late infection stages relative to the control samples, and to one another. Standard Sulfolobus cas gene annotations are employed [26].
| host gene ID | cas/cmr genes | amino acids | log2 fold changes | ||
|---|---|---|---|---|---|
| spacer acquisition | early | late | late/early | ||
| SiRe_0761 | cas1 | 290 | + 3.4 | ||
| I-A interference | |||||
| SiRe_0769 | cas3’ | 501 | + 2.7 | + 1.9 | |
| SiRe_0770 | cas3ʹ’ | 236 | + 2.5 | + 2.1 | |
| SiRe_0768 | cas5 | 240 | + 3.1 | + 2.0 | |
| SiRe_0772 | cas6 | 298 | + 2.7 | + 2.1 | |
| SiRe_0767 | cas7 | 321 | + 2.4 | ||
| SiRe_0771 | cas8’ | 345 | + 2.8 | + 2.0 | |
| SiRe_0766 | cas8ʹ’ | 143 | + 1.6 | + 2.9 | |
| III-B Cmr-β interference | |||||
| SiRe_0602 | cmr4 | 286 | −1.2 | ||
| SiRe_0601 | cmr5 | 155 | −1.7 | −1.2 | |
| SiRe_0599 | cmr6 | 283 | −1.4 | −1.1 | |
| CRISPR-115 locus 1 | + 3.2 | ||||
| CRISPR-93 locus 2 | + 2.3 | ||||