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Genomic organization of type I-C and type II-A CRISPR-Cas loci in S. pyogenes SF370. The CRISPR array consists of the leader (thick grey line), the repeats (black boxes), and the spacers (colored diamonds). The cas genes are represented in light blue, flanking genes are shown in grey and tracrRNA is shown in red. The color of the spacers corresponds to the putative function of their predicted targets (protospacers), as indicated in the legend.
