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. 2019 Mar 30;16(6):846–859. doi: 10.1080/15476286.2019.1593744

Figure 6.

Figure 6.

Origination and evolution of MIR12112 genes. (A) Locations of Sin-MIR12112s (black arrows) and a partial sequence of Sin-MIR12112 (red arrow) on pseudomolecules (LG6 and LG14, green boxes) of the S. indicum genome assembly. The schematic diagram of two homologous genome blocks (yellow) was adapted from Wang et al [47] . Transcription direction of Sin-MIR12112s is shown by black arrowheads. (B) Multiple sequence alignment of S. miltiorrhiza Smi-MIR12112 precursors and SmPPOs. The sense orientation of Smi-miR12112a and Smi-miR12112b foldback arms, the antisense strand of Smi-miR12112a* and Smi-miR12112b* foldback arms, and parts of the antisense strand of Smi-miR12112-targeted SmPPO5, SmPPO7 and SmPPO8 are shown. The red box indicates mature Smi-miR12112a and Smi-miR12112b sequences.