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. Author manuscript; available in PMC: 2020 Sep 23.
Published in final edited form as: Anal Chim Acta. 2019 May 4;1072:75–80. doi: 10.1016/j.aca.2019.05.001

Figure 3.

Figure 3.

Illustration of the nicking enzyme-assisted, signal-amplifiable detection of mercuric ion based on UCNPs. In the absence of Hg2+, the process stops at step 2 without hybridization between DNA_1 and DNA_mismatch, and no nicking occurs.