. Author manuscript; available in PMC: 2019 Jun 3.

Published in final edited form as: Cell Rep. 2018 May 29;23(9):2643–2652. doi: 10.1016/j.celrep.2018.04.118

Table 1.

Eye Phenotypes and Maternal Genotypes of RBP4 p.K12del Homozygous Offspring

Dam Genotype	Microphthalmia in del/del Offspring
Dam Genotype	Present	Absent
Homozygote (del/del)	17	1^a
Carrier (del/+)	0	9
Unknown (del/−)	0	1
Total	17	11

Sire genotypes were del/+ for 12 microphthalmic dogs and del/− for 5 dogs. For non-microphthalmic dogs, sire genotypes were del/+ for 7 dogs and del/− for 4 dogs. The skewed distribution of maternal genotypes in this retrospective analysis is highly significant (p < 10⁻⁶, Fisher’s exact test, df = 1).

Chorioretinal hypoplasia with normal globe size.