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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Autism Res. 2019 Apr 10;12(6):967–975. doi: 10.1002/aur.2105

Table 4.

Stratum-specific effect estimates for maternal diabetes and hypertensive disorders for three strata of maternal pre-pregnancy BMI in SEED

Model / Strata ASD vs. POP aOR (95% CI) p-value for interaction DD vs. POP aOR (95% CI) p-value for interaction
Maternal Diabetes
BMI: low, normal (<25 kg/m2)a 0.95 [0.71, 1.27] Reference 1.23 [0.97, 1.57] Reference
BMI: overweight (25-<30 kg/m2)a 0.99 [0.71, 1.37] 0.874 0.94 [0.69, 1.28] 0.1833
BMI: obese (≥30 kg/m2)a 1.10 [0.80, 1.52] 0.523 1.08 [0.79, 1.57] 0.522
Maternal Hypertensive Disorders
BMI: low, normal (<25 kg/m2) b 1.33 [1.06, 1.67] Reference 1.36 [1.10, 1.68] Reference
BMI: overweight (25-<30 kg/m2)b 1.23 [0.93, 1.64] 0.687 1.31 [1.00, 1.72] 0.840
BMI: obese (≥30 kg/m2)b 1.17 [0.89, 1.53] 0.479 1.12 [0.86, 1.46] 0.263
a.

Adjusted for maternal age, race/ethnicity, maternal education, maternal smoking, and study site.

b.

Adjusted for above (a.) plus plurality and parity.