Table 2.
Bone Parameters
| NNaD | LNaD | |
|---|---|---|
| Bone Mineral Density | ||
| Femoral cortical vBMD (g/cm3) | 1.266 ± 0.067 | 1.206 ± 0.058* |
| Vertebral Trabecular vBMD (g/cm3) | 0.704 ± 0.077 | 0.712 ± 0.112 |
| Bone Microachitecture | ||
| Cortical Thickness (mm) | 0.69 ± 0.04 | 0.69 ± 0.02 |
| Anterior-Posterior diameter (mm) | 3.60 ± 0.12 | 3.49 ± 0.11* |
| Cortical Mechanical Properties | ||
| Stiffness (N/mm) | 417.91 ± 27.82 | 377.58 ± 45.27* |
| Ultimate Load (N) | 151.86 ± 10.52 | 146.55 ± 10.79 |
| Energy to Fail (MPa) | 22.45 ± 4.80 | 21.02 ± 5.04 |
| Young’s Modulus (GPa) | 1.16 ± 0.05 | 1.12 ± 0.15 |
| Vertebral Compression | ||
| Stiffness (N/mm) | 719.07 ± 201.13 | 583.67 ± 80.20 |
| Failure Stress (MPa) | 40.58 ± 6.30 | 36.23 ± 5.23 |
| Energy to Fail (MPa) | 2.76 ± 0.95 | 2.69 ± 1.06 |
| Young’s Modulus | 740.22 ± 225.56 | 646.15 ± 199.98 |
| Static Histomorphometry | ||
| % Bone Surface (BS/BV) | 32.31 ± 2.54 | 36.59 ± 6.92 |
| Trabecular Separation (μm) | 0.29 ± 0.05 | 0.23 ± 0.05* |
| Trabecular Number | 2.47 ± 0.28 | 2.67 ± 0.40 |
| Dynamic Histomorphometry | ||
| MS/BS (%) | 23.31 ± 6.06 | 19.91 ± 6.18 |
| Mineral Apposition Rate (μm/day) | 1.96 ± 0.31 | 1.89 ± 0.23 |
| BFR/BS (μm/day/mm) | 0.02 ± 0.01 | 0.01 ± 0.01 |
| BFR/BV (μm/day/mm2) | 0.61 ± 0.30 | 0.43 ± 0.18 |
| Decalcified Histology | ||
| Osteoclasts/OC. Surface (1/mm) | 19.10 ± 4.35 | 12.58 ± 10.64 |
| Bone Mineralization | ||
| Peak Grey Level | 169.30 ± 8.78 | 177.25 ± 8.78 |
*
p<0.05 compared to the normal Na Diet.