Table 3.
Associations between anthropometrics, clinical risk factors, and current or recent osteoporosis treatment in women eligible for treatment, according to SvOS guidelines
| Variables | Crude OR | 95% CI | p | Adjusted OR | 95% CI | p |
|---|---|---|---|---|---|---|
| Age | 1.00 | 0.91–1.09 | 0.93 | 0.99 | 0.90–1.09 | 0.81 |
| Height | 1.00 | 1.00–1.00 | 0.86 | 1.00 | 1.00–1.00 | 0.26 |
| Weight | 0.99 | 0.98–1.00 | 0.13 | 1.17 | 0.96–1.43 | 0.13 |
| Body mass index | 0.97 | 0.93–1.01 | 0.10 | 0.93 | 0.88–0.98 | 0.01 |
| Level of education | 1.29 | 0.90–1.84 | 0.16 | 1.11 | 0.76–1.60 | 0.60 |
| Living alone | 1.04 | 0.78–1.38 | 0.81 | 0.99 | 0.73–1.34 | 0.94 |
| Diabetes | 0.95 | 0.55–1.66 | 0.86 | 0.93 | 0.52–1.65 | 0.80 |
| Rheumatoid arthritis | 0.67 | 0.30–1.52 | 0.34 | 0.50 | 0.20–1.25 | 0.14 |
| Obesity | 1.10 | 0.70–1.74 | 0.68 | 2.12 | 1.10–4.10 | 0.02 |
| High blood pressure | 0.66 | 0.49–0.88 | 0.004 | 0.67 | 0.50–0.90 | 0.01 |
| Excessive alcohol | 1.44 | 0.28–7.47 | 0.66 | 1.53 | 0.28–8.45 | 0.63 |
| Current smoking | 1.19 | 0.66–2.13 | 0.57 | 1.21 | 0.65–2.24 | 0.54 |
| Previous fall | 1.32 | 0.98–1.79 | 0.07 | 1.18 | 0.86–1.62 | 0.30 |
| Prior fracture | 2.21 | 1.61–3.06 | < 0.001 | 2.58 | 1.84–3.61 | < 0.001 |
| Glucocorticoid treatment | 2.13 | 1.37–3.30 | 0.01 | 2.88 | 1.80–4.59 | < 0.001 |
| FRAX-score | ||||||
| MOF | 1.02 | 1.00–1.03 | 0.01 | 1.02 | 1.00–1.03 | 0.01 |
| HIP | 1.01 | 1.00–1.02 | 0.03 | 1.01 | 1.00–1.02 | 0.03 |
Backward stepwise linear regression was used to investigate the associations between variables and current or recent osteoporosis treatment. The results are presented as odds ratios (OR) with corresponding 95% confidence interval (CI) for the final model and the last given result for variables being dropped from the model. The models investigating FRAX-scores were adjusted for variables not included in the calculation of the investigated score (i.e., level of education, living alone, obesity, high blood pressure, and previous fall). p values below 0.05 was considered significant and are presented in italic numbers. Crude = non-adjusted models, adjusted = models adjusted for all presented variables, obesity = BMI ≥ 30, high blood pressure = above either 90 mmHg diastolic or 140 mmHg systolic, excessive alcohol = 21 drinks or more per week, previous fall = experienced a fall the last 12 months, prior fracture = fracture after the age of 50 at all locations except skull, glucocorticoid treatment = treatment with 5 mg per oral prednisolone or equal for more than 3 months
MOF major osteoporotic fracture, HIP hip fracture
A p value below 0.05 was considered significant