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. 2019 Jun 3;10:2408. doi: 10.1038/s41467-019-10440-5

Table 1.

Demographic characteristics

Male, N (%) Female, N (%) p-Valuesa
Total (N = 212) 96 (45%) 116 (55%)
Age (years), mean (SD) 50.7 (14.5) 50.7 (14.1)
Marital status 0.502
   Single 5 (5.2) 5 (4.3)
   Married 89 (91.7) 102 (93.1)
   Widowed 1 (1.0) 3 (2.6)
   Divorced 2 (2.1) 0 (0)
Education <0.005
   Illiterate 15 (15.5) 40 (34.5)
   Elementary school 19 (19.6) 28 (24.3)
   Middle school 30 (30.9) 14 (12.1)
   High school 19 (19.6) 17 (14.6)
   Junior college, college, & above 14 (14.4) 17 (14.5)
Anthropometrics
Body mass index, mean (SD) 23.6 (3.0) 23 (3.0) 0.185
Waist-to-hip ratio, mean (SD) 0.94 (0.07) 0.89 (0.08) <0.005
Android fat ratio, mean (SD) 12.5 (1.2) 9.9 (1.4) <0.005
Gynoid fat ratio, mean (SD) 15.9 (3.0) 17.7 (3.0) <0.005
Life style behaviors
Daily carbohydrate intake (g), median (IQR) 223.2 (114.6) 182.0 (74.6) <0.005
Daily fat intake (g), median (IQR) 29.6 (29.4) 30.7 (29.3) 0.999
Current smoker 71 (60.7) 0 (0) <0.005
Current alcohol drinker 81 (69.8) 38(29.9) <0.005
Antibiotics use (past 3 months) 15 (15.6) 15 (12.9) 0.717
Disease history
Metabolic syndromeb 16 (16.7) 19 (16.4) 0.999
Type 2 diabetesc 13 (20.0) 9 (10.6) 0.167
Hypertensiond 19 (19.8) 15 (13.0) 0.243
Biomarkers
Fasting blood glucose (mmol/L), mean (SD) 5.4 (1.6) 5.2 (0.9) 0.190
Insulin (pmol/L), mean (SD) 40.6 (22.0) 47.9 (20.5) 0.020
Total cholesterol (mmol/L), mean (SD) 5.0 (0.9) 5.0 (0.8) 0.992
Triglycerides (mmol/L), mean (SD) 1.7 (1.2) 1.4 (1.5) 0.146
Low-density lipoprotein (mmol/L), mean (SD) 2.8 (0.7) 2.7 (0.7) 0.390
Hight-density lipoprotein (mmol/L), mean (SD) 1.5 (0.4) 1.7 (0.4) <0.005

ap-values are from chi-square tests for categorical variables and t tests for continuous variables by comparing the characteristics between men and women

bMetabolic syndrome was defined using International Diabetes Federation criteria for the Chinese population, all the measurements were taken at the baseline at the same time the stool samples were collected

cType 2 diabetes was defined as HbA1c ≥ 6.4%

dHypertension was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg