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. 2019 Jun 3;9:8189. doi: 10.1038/s41598-019-44733-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of KDM5A and LSD2 gene silencing on cell viability. (A) A498 cells (B) ACHN cells. Scrambled siRNA, KDM5A or LSD2 siRNA were used to transfect the cells for 48 hours. MTT assay was used for the assessment of cell viability. Values are expressed in comparison to control cells, which were defined as 100%. Results were analyzed by one-way ANOVA followed by the Bonferroni post hoc correction. (*P < 0.05; **P < 0.01, ***P < 0.001; *in comparison to control, # in comparison to scrambled.