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. 2019 May 28;10:1185. doi: 10.3389/fimmu.2019.01185

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Copyright © 2019 Guo, Hong, Wang, Zhang, Tang, Wu, Chu, Liu, He, Yang, Yin and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum and mucosal antibody responses after oral therapeutic immunization. (A) Serum IgG against H. pylori lysates. (B) Serum IgA against H. pylori lysates. (C) Gastric and intestinal sIgA against H. pylori lysates. Data are mean ± S.D. p < 0.05 was considered as statistically significant. *p < 0.05, **p < 0.01, ***p < 0.001, ns, not significant.