Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 28;10:512. doi: 10.3389/fgene.2019.00512

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Duan, Jiang, Alqahtani, Mandoiu, Dong, Zheng, Marjani, Chen and Tian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Pairwise comparisons of methylomes between consecutive development stages and DMRs in gametes. Histogram (A) of the numbers of stable (dark blue) and changing (sky blue) tiles between consecutive stages. Histogram of the numbers of decreasing (gray) and increasing (pink) tiles between consecutive stages. The numbers (B) of DMRs and corresponding genes between gametes of different types. Pie plots (C) of the distribution of in vivo MII- and sperm-specific DMRs in annotated genomic regions. Box plots (D) of DNA methylation levels of oocyte- (upper left) or sperm- (upper right) specific DMRs in gametes and early embryos, as well as distributions of tiles hypomethylated (≤25%; bottom left) and hypermethylated (≥75%; bottom right) tiles in both gametes in each development stage. GV, germinal vesicle oocytes; MII, matured oocytes.