eTable 2. Search string*.

EMBASE	“transsexualism” OR “transgender” OR “transgenderism” AND (“reassignment surgery” OR “sex reassignment”) AND “quality of life”
PsycINFO	(DE “Transgender” OR DE “Transsexualism” OR DE “Gender Identity Disorder”) AND (DE “Sex Change” OR DE “Surgery” OR “reassignment surgery” OR “sex reassignment”) AND “quality of life”
PubMed 1. Catch phrase search (MeSH terms) 2. Key word search	(“Transsexualism”[Mesh]) AND (“Sex Reassignment Surgery”[Mesh]) AND (“Quality of Life”[Mesh]) ((“Transgender Persons”[Mesh]) OR “Transsexualism”[Mesh]) AND (“Quality of Life”[Mesh]) (“Quality of life”) AND (“gender reassignment surgery” OR “sex reassignment operation” OR “gender transformation operation” OR “sex reassignment surgery” OR “penile inversion vaginoplasty” AND sex* AND chang* OR sex* AND reassign* OR gender-reassign*) AND (gender-dysphor* OR transsex* OR gender-nonconform* OR gender-non-conform* OR transgend* OR transident* OR gender-incongruence OR gender-varian* OR gender-transform* OR gender-identity-disorder* OR sexual-transition OR gender-transition OR sexual-dysphor* OR transvest* OR autogyn* OR trans-sex* OR trans-gend* OR trans-ident* OR “male-to-female”)
Web of Science	(gender-dysphor* OR transsex* OR gender-nonconform* OR gender-non-conform* OR trans-gend* OR trans-ident* OR gender-incongruence OR gender-varian* OR gender-transform* OR gender-identity-disorder* OR sexual-transition OR gender-transition OR sexual-dysphor* OR transvest* OR autogyn* OR trans-sex* OR trans-gend* OR trans-ident* OR “male-to-female”) AND (“gender reassignment surgery” OR “sex reassignment operation” OR “gender transformation operation” OR “sex reassignment surgery” OR “penile inversion vaginoplasty” OR sex* chang* OR sex* reassign* OR gender-reassign*) AND (“quality of life”)

* Catch phrases and key words used in the literature search