Table 1.
Prophage content of the 106 GBS strains, determination of prophage A insertion sites.
Prophage group | A | B | C | D | E | F | ||||
---|---|---|---|---|---|---|---|---|---|---|
Prophage A insertion sites | IS A1 | IS A2 | IS A3 | IS A4 | ||||||
All strains for 2002–2018 (n = 106) | 46 (43.4) | 3 | 11 | 7 | 25 | 10 (9.4) | 13 (12.3) | 8 (7.5) | 14 (13.2) | 17 (16.0) |
EOD (n = 58) | 22 (37.9) | 3 | 6 | 2 | 11 | 2 (3.4) | 7 (12.1) | 3 (5.1) | 8 (13.8) | 12 (20.7) |
2002–2010 (n = 43) | 11 (25.6) | 1 | 2 | 2 | 6 | 1 (2.3) | 6 (13.9) | 2 (4.6) | 5 (11.6) | 9 (20.9) |
2011–2018 (n = 15) | 11 (73.3) | 2 | 4 | 5 | 1 (6.7) | 1 (6.7) | 1 (6.7) | 3 (20.0) | 3 (20.0) | |
LOD (n = 48) | 24 (50.0) | 5 | 5 | 14 | 8 (16.7) | 7 (14.6) | 5 (10.4) | 6 (12.5) | 5 (10.4) | |
2002–2010 (n = 34) | 13 (38.2) | 5 | 1 | 7 | 5 (14.7) | 5 (14.7) | 4 (11.8) | 4 (11.8) | 3 (8.8) | |
2011–2018 (n = 14) | 11 (78.6) | 4 | 7 | 3 (21.4) | 2 (14.3) | 1 (7.1) | 2 (14.3) | 2 (14.3) | ||
Fetal-neonatal death (n = 13) | 5 (38.5) | 4 | 1 | 1 (7.7) | 2 (15.4) | 2 (15.4) | ||||
Bacteremia (n = 50) | 23 (46.0) | 3 | 2 | 4 | 14 | 7 (14.0) | 9 (18.0) | 5 (10.0) | 6 (12.0) | 11 (22.0) |
Early (n = 31) | 15 (48.4) | 3 | 2 | 2 | 8 | 2 (6.5) | 5 (16.1) | 1 (3.2) | 4 (12.9) | 6 (19.4) |
Late (n = 19) | 8 (42.1) | 2 | 6 | 5 (26.3) | 4 (21.1) | 4 (21.1) | 2 (10.5) | 5 (26.3) | ||
Meningitis (n = 43) | 18 (41.9) | 5 | 3 | 10 | 2 (4.6) | 4 (9.3) | 2 (4.6) | 6 (14.0) | 3 (7.0) | |
Early (n = 14) | 2 (14.3) | 2 | 2 (14.3) | 1 (7.1) | 2 (14.3) | 2 (14.3) | ||||
2002–2010 (n = 13) | 1 (7.7) | 1 | 2 (15.4) | 1 (7.1) | 2 (15.4) | 2 (15.4) | ||||
2011–2018 (n = 1) | 1 (100.0) | 1 | 2 (14.3) | 1 (7.1) | 2 (14.3) | 2 (14.3) | ||||
Late (n = 29) | 16 (55.2) | 5 | 3 | 8 | 2 (6.9) | 2 (6.9) | 1 (3.4) | 4 (13.8) | 1 (3.4) | |
2002–2010 (n = 21) | 9 (42.9) | 5 | 4 | 1 (4.8) | 2 (9.5) | 1 (4.8) | 2 (9.5) | 1 (4.8) | ||
2011–2018 (n = 8) | 7 (87.5) | 3 | 4 | 1 (12.5) | 2 (25.0) | |||||
CC1 (n = 10) | 8 (80.0) | 8 | 3 (30.0) | |||||||
CC17 (n = 50) | 26 (52.0) | 1 | 1 | 5 | 19 | 9 (18.0) | 11 (22.0) | 5 (10.0) | 1 (2.0) | 5 (10.0) |
2002–2010 (n = 34) | 13 (38.2) | 1 | 1 | 1 | 10 | 5 (14.7) | 9 (26.5) | 4 (11.8) | 2 (5.9) | |
2011–2018 (n = 16) | 13 (81.2) | 4 | 9 | 4 (25.0) | 2 (12.5) | 1 (6.2) | 1 (6.2) | 3 (18.7) | ||
CC19 (n = 12) | 3 (25.0) | 2 | 1 | 1 (8.3) | 2 (16.7) | 2 (16.7) | 3 (25.0) | 1 (8.3) | ||
CC23 (n = 25) | 7 (28.0) | 1 | 1 | 5 | 1 (4.0) | 10 (40.0) | 4 (16.0) | |||
Other CCs (n = 9) | 2 (22.2) | 1 | 1 | 4 (44.4) |
Number of characterized strains with at least one prophage in their genome (%), by prophage group.