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. 2019 May 28;10:548. doi: 10.3389/fphar.2019.00548

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Copyright © 2019 Li, Shen, Wu, Kuang, Liu, Cheng, Pu, Chen, Li, Li, Zou, Zhang, Jiang, Qu and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intestinal Abcg5 and Abcg8 levels were increased in Irisin-ApoE-/- mice. (A,B) mRNA expression of cholesterol transporters in duodenum, jejunum, and ileum of mice (n = 6). (C,D) Protein expression of Abcg5 and Abcg8 in the ileum (n = 3) and (E) fecal cholesterol output in mice (n_WT = 6, n_TG = 4, n_WTD-WT = 6, n_WTD-TG = 6). Data are mean ± SEM. ^∗P < 0.05.