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. 2019 May 28;10:666. doi: 10.3389/fphys.2019.00666

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Copyright © 2019 Monasky, Micaglio, Ciconte, Benedetti, Di Resta, Vicedomini, Borrelli, Ghiroldi, Piccoli, Anastasia, Santinelli, Ferrari and Pappone.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Electrocardiograms of proband and family members at baseline and after ajmaline challenge. Proband’s father (II-7), proband (III-3), and proband’s youngest sister (III-6) exhibit the BrS type 1 pattern after ajmaline administration, confirming the BrS diagnosis. Proband’s second eldest sister (III-2) and brothers (III-4 and III-5) are ajmaline negative.