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. 2019 May 28;10:574. doi: 10.3389/fphar.2019.00574

Table 3.

Logistic regression models for pathological complete response in the training and testing datasets.

Univariate model
Multivariate model
OR 95% CI P-value OR 95% CI P-value
Training set
lncRNA predictive score 2.72 2.06–3.64 4.49 × 10-12 1.60 1.06–2.44 2.65 × 10-2
Grade (ref = 1)
2 2.10 0.39–39.00 4.84 × 10-1 0.50 0.07–10.30 5.54 × 10-1
3 12.32 2.56–221.60 1.44 × 10-2 1.51 0.20–31.29 7.25 × 10-1
ER (ref = negative)
Positive 0.22 0.14–0.36 8.38 × 10-10 0.82 0.35–1.87 6.41 × 10-1
PAM 50 subtypes (ref = Basal-like)
Her2+ 0.43 0.16–0.98 5.83 × 10-2 0.50 0.13–1.53 2.57 × 10-1
Luminal A 0.06 0.02–0.14 4.51 × 10-9 0.26 0.06–0.95 5.12 × 10-2
Luminal B 0.34 0.16–0.65 1.96 × 10-3 0.92 0.32–2.69 8.85 × 10-1
Testing set
lncRNA predictive score 2.69 2.09–3.51 6.44 × 10-14 1.83 1.27–2.67 1.33 × 10-3
Grade (ref = 1)
2 3.21 0.63–58.67 2.63 × 10-1 1.48 0.27–27.67 7.13 × 10-1
3 13.95 2.93–250.25 1.00 × 10-2 2.75 0.51–51.32 3.42 × 10-1
ER (ref = negative)
positive 0.19 0.12–0.29 1.11 × 10-13 0.41 0.20–0.85 1.52 × 10-2
PAM 50 subtypes (ref = Basal-like)
Her2+ 0.97 0.49–1.87 9.18 × 10-1 1.38 0.63–2.99 4.15 × 10-1
Luminal A 0.05 0.01–0.13 4.60 × 10-7 0.30 0.06–1.05 8.27 × 10-2
Luminal B 0.28 0.17–0.44 3.84 × 10-8 1.02 0.48–2.16 9.56 × 10-1