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. 2019 May 21;18(1):846–855. doi: 10.3892/ol.2019.10380

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Figure 1. — Expression of Twist1 in astrocytoma tissues. (A) Twist1 was weakly expressed in diffuse astrocytomas and localized to the cytoplasm. (B) Twist1 was moderately expressed in anaplastic astrocytomas and localized to the cytoplasm. (C) Glioblastoma tissues exhibited strong, positive Twist1 expression, localized in the nucleus and/or the cytoplasm. Magnification, ×200. (D) HSCOREs of diffuse astrocytoma, anaplastic astrocytoma and glioblastoma tissues. **P<0.05, vs. the diffuse astrocytoma group; ^##P<0.05, vs. the anaplastic astrocytoma group. Twist, Twist family bHLH transcription factor 1; HSCORE, histological score.