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. 2019 May 20;18(1):720–732. doi: 10.3892/ol.2019.10378

Table II.

The clinical and radiological characteristics of patients in the training and validation cohorts.

A, Clinical characteristics

Training cohort (n=99) Validation cohort (n=43)


Characteristic MP (n=37) MN (n=62) P-valuea MP (n=16) MN (n=27) P-valuea P-valueb
Sex 0.931c 0.723c 0.805c
  Male 32 54 15 23
  Female   5   8   1   4
Mean age ± SD, years 57.49±9.56 56.45±9.71 0.607e 55.88±8.63 55.41±8.00 0.858e 0.456e
AFP, ng/ml 0.025c 0.038c 0.715c
  ≤7   9 32   5 16
  7–400 17 20   5   9
  >400 11 10   6   2
Location 0.561c 0.372c 0.581c
  Right 31 49 10 23
  Left   6 13   6   4
HBsAg 0.325c 0.614c 0.668c
  Positive 26 49 12 22
  Negative 11 13   4   5
HCV-Ab 1.000c 1.000d 0.989c
  Positive   1   3   0   1
  Negative 36 59 16 26
Differentiation 0.026c 0.034d 0.565c
  Well   2   3   0   4
  Moderate 19 47   9 20
  Poor 16 12   7   3

B, Radiological characteristics

Training cohort (n=99) Validation cohort (n=43)


Characteristic MP (n=37) MN (n=62) P-valuea MP (n=16) MN (n=27) P-valuea P-valueb

MTD, cm 3.82±0.88 3.21±0.94 0.002e 3.75±0.80 2.92±0.62 <0.001e 0.231e
Background liver 0.690c 0.358c 0.553c
  Noncirrhosis 14 21   3 10
  Cirrhosis 23 41 13 17
Tumor encapsulation 0.805c 0.362c 0.534c
  Absent 11 17   2   8
  Present 26 45 14 19
Fast wash-in 0.292c 0.929c 0.742c
  Yes 30 55 14 22
  No   7   7   2   5
Fast wash-out 0.409c 0.534c 0.720c
  Yes 24 35 11 16
  No 13 27   5 11
Tumor necrosis 0.638c 0.372c 0.668c
  Absent 29 46 11 23
  Present   8 16   5   4

MP, microvascular invasion-positive; MN, microvascular invasion-negative; AFP, α-fetoprotein; HBsAg, hepatitis B surface antigen; MTD, maximum tumor diameter; HCV-Ab, hepatitis C antibody.

a

MP vs. MN

b

Training cohort vs. validation cohort

c

P-values calculated using the χ2 test

d

P-values calculated using Fisher's exact test

e

P-values calculated using the independent t-test.