Table II.
A, Clinical characteristics | |||||||
---|---|---|---|---|---|---|---|
Training cohort (n=99) | Validation cohort (n=43) | ||||||
Characteristic | MP (n=37) | MN (n=62) | P-valuea | MP (n=16) | MN (n=27) | P-valuea | P-valueb |
Sex | 0.931c | 0.723c | 0.805c | ||||
Male | 32 | 54 | 15 | 23 | |||
Female | 5 | 8 | 1 | 4 | |||
Mean age ± SD, years | 57.49±9.56 | 56.45±9.71 | 0.607e | 55.88±8.63 | 55.41±8.00 | 0.858e | 0.456e |
AFP, ng/ml | 0.025c | 0.038c | 0.715c | ||||
≤7 | 9 | 32 | 5 | 16 | |||
7–400 | 17 | 20 | 5 | 9 | |||
>400 | 11 | 10 | 6 | 2 | |||
Location | 0.561c | 0.372c | 0.581c | ||||
Right | 31 | 49 | 10 | 23 | |||
Left | 6 | 13 | 6 | 4 | |||
HBsAg | 0.325c | 0.614c | 0.668c | ||||
Positive | 26 | 49 | 12 | 22 | |||
Negative | 11 | 13 | 4 | 5 | |||
HCV-Ab | 1.000c | 1.000d | 0.989c | ||||
Positive | 1 | 3 | 0 | 1 | |||
Negative | 36 | 59 | 16 | 26 | |||
Differentiation | 0.026c | 0.034d | 0.565c | ||||
Well | 2 | 3 | 0 | 4 | |||
Moderate | 19 | 47 | 9 | 20 | |||
Poor | 16 | 12 | 7 | 3 | |||
B, Radiological characteristics | |||||||
Training cohort (n=99) | Validation cohort (n=43) | ||||||
Characteristic | MP (n=37) | MN (n=62) | P-valuea | MP (n=16) | MN (n=27) | P-valuea | P-valueb |
MTD, cm | 3.82±0.88 | 3.21±0.94 | 0.002e | 3.75±0.80 | 2.92±0.62 | <0.001e | 0.231e |
Background liver | 0.690c | 0.358c | 0.553c | ||||
Noncirrhosis | 14 | 21 | 3 | 10 | |||
Cirrhosis | 23 | 41 | 13 | 17 | |||
Tumor encapsulation | 0.805c | 0.362c | 0.534c | ||||
Absent | 11 | 17 | 2 | 8 | |||
Present | 26 | 45 | 14 | 19 | |||
Fast wash-in | 0.292c | 0.929c | 0.742c | ||||
Yes | 30 | 55 | 14 | 22 | |||
No | 7 | 7 | 2 | 5 | |||
Fast wash-out | 0.409c | 0.534c | 0.720c | ||||
Yes | 24 | 35 | 11 | 16 | |||
No | 13 | 27 | 5 | 11 | |||
Tumor necrosis | 0.638c | 0.372c | 0.668c | ||||
Absent | 29 | 46 | 11 | 23 | |||
Present | 8 | 16 | 5 | 4 |
MP, microvascular invasion-positive; MN, microvascular invasion-negative; AFP, α-fetoprotein; HBsAg, hepatitis B surface antigen; MTD, maximum tumor diameter; HCV-Ab, hepatitis C antibody.
MP vs. MN
Training cohort vs. validation cohort
P-values calculated using the χ2 test
P-values calculated using Fisher's exact test
P-values calculated using the independent t-test.