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Results of this study that included cohorts from 4 countries suggest that the association between genetically elevated lipoprotein(a) (Lp[a]) levels and calcific aortic valve stenosis (CAVS) is comparable in patients with coronary artery disease (CAD) vs those without and that first-degree relatives of patients with high Lp(a) levels and CAVS may have higher aortic valve calcification and could be at higher future risk of aortic valve calcification or CAVS.
